Hypersomnia

On this page, we summarize our current research projects on the topic of Hypersomnia. We specifically investigate:

  • The underlying mechanisms of narcolepsy (NT1 and NT2) and idiopathic hypersomnia (IH).

Narcolepsy and Idiopathic Hypersomnia

Pathophysiology of Narcolepsy and Idiopathic Hypersomnia: A Multimodal Neuroimaging Study

Summary

Narcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence, characterized by excessive daytime sleepiness, which impacts sleep and daytime functioning. They are frequent neurological disorders of sleep, with a prevalence of 0.05% (for narcolepsy) to 0.3% (for IH), which is 15 to 100 times more than multiple sclerosis and Parkinson’s disease. To date, the mechanisms underlying central hypersomnias are poorly understood. Moreover, the precise impacts of these disorders on cognitive function (e.g., attention, memory) have not been studied thoroughly. With the help of neuroimaging methods (electroencephalography – EEG, magnetic resonance imaging – MRI, and polysomnography sleep recording), we aim to identify the non-invasive neural biomarkers and mechanisms characterizing each phenotype of narcolepsy and IH.

Need more info?

Please contact hypersomnia.research@gmail.com

or

Elizaveta Frolova at science2204@gmail.com

Narcolepsy and Idiopathic Hypersomnia

Narcolepsy and Idiopathic Hypersomnia

Pathophysiology of Narcolepsy and Idiopathic Hypersomnia: A Multimodal Neuroimaging Study

Summary

Narcolepsy and idiopathic hypersomnia are central disorders of hypersomnolence, characterized by excessive daytime sleepiness, which impacts sleep and daytime functioning. They are frequent neurological disorders of sleep, with a prevalence of 0.05% (for narcolepsy) to 0.3% (for IH), which is 15 to 100 times more than multiple sclerosis and Parkinson’s disease. To date, the mechanisms underlying central hypersomnias are poorly understood. Moreover, the precise impacts of these disorders on cognitive function (e.g., attention, memory) have not been studied thoroughly. With the help of neuroimaging methods (electroencephalography – EEG, magnetic resonance imaging – MRI, and polysomnography sleep recording), we aim to identify the non-invasive neural biomarkers and mechanisms characterizing each phenotype of narcolepsy and IH.

Need more info?

Please contact hypersomnia.research@gmail.com

or

Elizaveta Frolova at science2204@gmail.com